Assistant Professor
Department of Pediatrics
Genital herpes is the most common sexually transmitted viral infection in the United States. Better therapeutic approaches are needed to reduce genital herpes infection and its consequences in neonates. Our laboratory is currently focusing on identifying the viral immune evasion mechanisms important for reactivation of genital and neonatal infections. Our current work includes understanding how herpes simplex virus disrupts the function of T-cells that are recruited to the site of virus reactivation.
Selected Publications:
Han JY, Sloan DD, Aubert M, Miller SA, Dang CH, Jerome KR. Apoptosis and antigen receptor function in T and B cells following exposure to herpes simplex virus. Virology. 2007 Mar 15;359(2):253-63.
Sloan DD, Han JY, Sandifer TK, Stewart M, Hinz AJ, Yoon M, Johnson DC, Spear PG, Jerome KR. Inhibition of TCR signaling by herpes simplex virus. J Immunol. 2006 Feb 1;176(3):1825-33.
Other links
http://www.med.umn.edu/peds/id/faculty/hanjinyoung/home.html
http://www.uofmchildrenshospital.org/Services/Services/c_404978.asp